Ultima Nolva

Ultima Nolva

Manufacturer: Ultima Pharmaceuticals

Category: Oral

Dose and quantity: 20mg/pill

Package: 50 pills

Form:  Oral

Active Substance: Tamoxifen Citrate

Active Half-Life: 5-7 days

Classification: Selective Estrogen Receptor Modulator (SERM)

Dosage: 20-40 mg a day 

Water retention: No

Aromatization: No

Info: Nolvadex, also referred to as tamoxifen in its generic form, is primarily employed as a medication to treat and prevent breast cancer. It falls within the category of drugs known as selective estrogen receptor modulators (SERMs), which function by inhibiting the impact of estrogen in specific tissues. In the realm of bodybuilding, individuals often utilize anabolic steroids to augment muscle growth, strength, and overall performance. Nonetheless, the use of steroids can lead to the suppression of the body's natural hormone production, including testosterone, thereby disrupting hormonal equilibrium. Consequently, some bodybuilders contemplate incorporating tamoxifen (Nolvadex) into their post-cycle therapy (PCT) to address these concerns.
 

Effects:

Breast Cancer Treatment: Tamoxifen is widely used to treat both early and advanced breast cancer. It works by blocking the effects of estrogen on breast tissue, which can slow or stop the growth of cancer cells. In this regard, it has been effective in reducing the risk of cancer recurrence and improving survival rates in many breast cancer patients.

Breast Cancer Prevention: Tamoxifen has been shown to reduce the risk of developing breast cancer in women at high risk for the disease. High-risk individuals may include those with a family history of breast cancer or certain genetic mutations, like BRCA1 or BRCA2.

Reduction of Breast Cancer Risk in Contralateral Breast: For women who have already been diagnosed with breast cancer in one breast, tamoxifen can help reduce the risk of developing cancer in the opposite breast, known as contralateral breast cancer.

Treatment of Ductal Carcinoma In Situ (DCIS): Tamoxifen is often used as part of the treatment regimen for DCIS, a non-invasive form of breast cancer that affects the milk ducts. It can help prevent the recurrence of DCIS or its progression to invasive breast cancer.

Ovarian Cancer Risk Reduction: Some studies suggest that tamoxifen may reduce the risk of ovarian cancer in women who are at increased risk.

Fertility Preservation: In some cases, tamoxifen may be used to induce ovulation in women with infertility issues related to irregular ovulation, which can be a side effect of tamoxifen treatment.

Bone Health: Tamoxifen may have a positive effect on bone density and can help prevent osteoporosis, a condition characterized by weakened bones.
 

Adverse Effects:

Hot Flashes: Many individuals taking tamoxifen experience hot flashes, which are characterized by sudden and intense feelings of heat, sweating, and redness of the skin.

Mood Changes: Tamoxifen may cause mood swings, depression, or changes in mood and emotional well-being.

Vaginal Discharge and Dryness: Some women may experience vaginal discharge and dryness while taking tamoxifen, which can be uncomfortable.

Irregular Menstrual Periods: Tamoxifen can affect menstrual cycles, leading to irregular periods or even amenorrhea (absence of menstruation) in some women.

Nausea and Vomiting: Nausea and vomiting are possible side effects, although they are generally mild.

Fatigue: Some individuals may experience fatigue or a general feeling of tiredness while on tamoxifen.

Weight Changes: Tamoxifen can cause weight gain in some individuals.

Bone Health: Although tamoxifen can have a positive effect on bone density, it can also lead to bone loss in some cases.
 

Dosage and Duration:

In the treatment of metastatic breast cancer (cancer that has spread to other parts of the body), the typical dosage is 20 to 40 milligrams (mg) of tamoxifen citrate taken orally once a day. For the prevention of breast cancer in high-risk individuals, the typical dosage is 20 mg of tamoxifen citrate taken orally once a day. Treatment duration may vary, but it is often recommended for a period of five years.

The duration of tamoxifen treatment for breast cancer can vary depending on the stage and type of breast cancer, as well as individual factors. Treatment may be recommended for several years, and it is often taken for at least five years. Your healthcare provider will assess your response to treatment and may adjust the duration accordingly.
 

Combination with Other Drugs:

The use of tamoxifen citrate (Nolvadex) can be in combination with Hormone Therapy, Chemotherapy, Targeted Therapies, Fertility Medications, Bone Health Medications, Anticoagulants.